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diss. Brooers‎ CH30 163 164 HN~~NH 165 O NH2 158 253 Chapter 13 Engineering of Amphiphilic Block Copolymers for Drug and Gene Delivery 391 A) O PEO-b-PBLA CH3 O CH2 CH2 NH C CH NH H nm CH2 CO Hydrolysis, ester change O CH2 OO CH3 O CH2 CH2 NH C CH NH C CH2 CH NH H nxy CH2 CO CO R R H R PEO-b-p(L-Asp) PEO-b-p(n-butyl-L-Asp) PEO-b-p(lauryl-L-Asp) PEO-b-p(methynaphtyl-L-Asp) PEO-b-p(BLA, C16) B) R OCH2 CH3 orOH 3 R O CH2 CH3 or OH 11 O R CH2 R O CH2 CH3 15 or OH or OCH2 O PEO-b-PBLA CH3O CH2 CH2 O nCH2 SCH2 NH C CH NH H 3m Binxry CH2 C O CH2 O OO CH3OCH2CH2OCH2 SCH2NHCCHNHyCCHNH H n 3 PEO-b-PHHA R1 R2 NH CH2 OH 6 Khutsing C R1 O CH z 2 C R2 O PEO-b-PHSA O R1 H3C CH2 C O Brrokers‎ NH R2 HO Weeela) 16 6 NH 6 Figure13.

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