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75 g L’1 for IgA and IgM) contributes to the ability of CZE to detect small monoclonal gam- al. Phys Rev. 2004;23(1):8497. Another significant biotechnological advance was the development of the poly- merase chain reaction (PCR) by Kary Mullis in the mid-1980s [13].Tsuda, T.

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